formas sólidas compreendendo (1e, 4e)-2-amino-n,n-dipropil-8-(4-(pirrolidina-1-carbonil) fenil)-3h-benzo[b]azepina-4-carboxamida, composições das mesmas, e uso das mesmas
ANTHONY FRANK,ANTONIO C. FERRETTI,HON-WAH MAN,MARIE G. BEAUCHAMPS,TIMOTHY D. FITZPATRICK,XIAOLING LU,YING LI
申请号：
BR112017012646
公开号：
BR112017012646A2
申请日:
2015.12.15
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
Compositions are provided here, including the crystalline forms of (1E to 4e) - 2 - amino - N, N - dipropil - 8 - (4 - (pyrrolidine - 1 - carbonyl) phenyl) - 3H benzo [b] azepine - 4 - carboxamide (\"compound\"),Methods of preparing the crystalline forms, and methods of using the crystalline forms for the treatment of diseases, including, for example, cancer.são fornecidas aqui composições incluindo as formas cristalinas de (1e, 4e)-2-amino-n,n-dipropil-8-(4-(pirrolidina-1-carbonil) fenil)-3h-benzo[b]azepina-4-carboxamida ("composto a"), métodos de preparar as formas cristalinas, e métodos de usar as formas cristalinas para o tratamento de doenças, incluindo, por exemplo, câncer.
