A method for treating alopecia and/or hair depigmentation includes administering to a subject in need of such treatments a synthetic peptide, which has an amino acid sequence that has 20-44 amino acid residues and includes at least 20 consecutive residues that has at least 90% amino acid sequence identity to residues 16-35 of SEQ ID NO: 10. Also disclosed herein are pharmaceutical compositions containing the synthetic peptide； and uses thereof. According to various embodiments of the present disclosure, the synthetic peptide is useful in treating alopecia and/or hair depigmentation in a subject.Cette invention concerne un peptide synthétique dérivé du PEDF comportant de 20 à 44 résidus acide aminé, des compositions pharmaceutiques le contenant et leur utilisation. Le peptide est utile pour traiter l'alopécie et/ou la dépigmentation capillaire chez un sujet.
