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LIPOSOME FORMULATIONS
专利权人:
LLC;OPKO Pharmaceuticals
发明人:
Arturo SANTOS,Phillip FROST
申请号:
US16712261
公开号:
US20200163877A1
申请日:
2019.12.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to pharmaceutical formulations comprising an anti angiogenic compound such as a monoclonal antibody or fragment thereof selected from, for example, ranibizumab, which is a vascular endothelial growth factor binder which inhibits the action of VEGF, and a delivery agent selected from a pharmaceutically acceptable liposome. The formulations are useful in the treatment of a variety of angiogenic disorders and diseases in animals and people, and, preferably, in ophthalmic disorders selected from age-related macular degeneration diabetic macular edema and corneal neovascularization.
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