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Multi-leu peptides and analogues thereof as selective PACE4 inhibitors and effective antiproliferative agents
专利权人:
LA SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA-SCIENCES SANTE ET HUMAINES S.E.C.
发明人:
Robert Day,Martin Fugére,Witold A. Neugebauer
申请号:
US14149857
公开号:
US09573974B2
申请日:
2014.01.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed herein are PACE4 inhibitors, compositions comprising PACE4 inhibitors and their uses thereof for lowering PACE4 activity, reducing cell proliferation, reducing tumor growth, reducing metastasis formation, preventing and/or treating cancer. Also provided are methods for lowering PACE4 activity, reducing the proliferation of a cell, reducing tumor growth and/or treating and preventing cancer. Methods for screening PACE4 inhibitors and cell proliferation inhibitors are further provided.
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来源网址:
http://www.ckcest.cn/home/
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