Agents selected from: (i) a C1-C24 alkyl ester of a saturated or cis-unsaturated C10-C24 fatty acid (ii) a monoester or polyester of a polyol having at least four hydroxy groups with a saturated or cis-unsaturated C10-C24 fatty acid or an anhydro derivative thereof (iii) a monoester or polyester of a mono-, di- or poly-saccharide with a saturated or cis-unsaturated C10-C24 fatty acid (iv) an amide of a saturated or cis-unsaturated C10-C24 fatty acid with an aliphatic or aromatic amine or with an amino acid, peptide, protein or aminosaccharide and (v) combinations of any of (i) to (iv), can be used for treatment of autoimmune diseases and other immune-associated inflammatory disorders. Preferred agents are ethyl oleate and mannide monooleate or a combination thereof.
