ХЭМЛИН Дэвид (US),МАДЖЕТИ Сатянараяна (US),ПЕТРШКОВСКИ Збигнев (US)
申请号：
RU2011123733/15
公开号：
RU2011123733A
申请日:
2009.11.13
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A method of at least increasing oral moisturization and relieving hyposalivation-related symptoms, comprising: preparing a topical composition for oral administration, which comprises, as a salivating agent, a combination of grape seed extract and citrus fruit extract, the combination being effective as stimulating salivation and is present in a concentration effective to relieve the symptom or to increase the hydration of the oral cavity； teaching test results, which indicate that the extract of grape seed extract and citrus fruits provides relief from a symptom or increase oral moistening； and the presentation of the composition along with the test result. 2. The method according to claim 1, wherein the hyposalivation-related symptom is selected from the group consisting of: dry mouth, bad breath, thick saliva, altered taste and difficulty in speaking or swallowing. The method according to claim 1, wherein the topical composition is selected from the group consisting of chewing gum, a soluble strip, a tablet, a troche, a mouthwash, a spray, a toothpaste, an ointment, a foam, a salivary booster, and a powder that is optionally impregnated with a carrier .4. The method according to claim 1, wherein the grape seed extract and citrus fruit extract are present in synergistic amounts. The method according to claim 1, wherein the grape seed extract and citrus fruit extract are present in a concentration equal to or less than 1 wt.% Of the topical composition. The method according to claim 1, in which to1. Способ по меньшей мере увеличения увлажнения полости рта и освобождения от симптома, связанного с гипосаливацией, содержащий:составление топической композиции для перорального введения, которая включает в качестве стимулирующего слюноотделение средства комбинацию экстракта виноградных косточек и экстракта плодов цитрусовых, причем комбинация является эффективной в качестве стимулирующего слюноотделение средства и присутствует в концентрации, эффективной для освобожде
