Wisconsin Alumni Research Foundation;The Trustees of Princeton University
发明人:
Yibin Kang,Yongna Xing,Liling Wan,Feng Guo
申请号:
US16406837
公开号:
US10786545B2
申请日:
2019.05.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.