The present invention relates to a microneedle device, which comprises a substrate, microneedles disposed on the substrate, and physiologically active composition attached on the microneedles and/or on the substrate. The physiologically active composition contains at least one type of polyhydric alcohol selected from glycerol, ethylene glycol, propylene glycol, and 1,3-butanediol, and physiologically active substance, and substantially contains no water. The present invention relates to a microneedle device, which comprises a substrate, microneedles disposed on the substrate, and physiologically active composition attached on the microneedles and/or on the substrate. The physiologically active composition contains at least one type of polyhydric alcohol selected from glycerol, ethylene glycol, propylene glycol, and 1,3-butanediol, and physiologically active substance, and substantially contains no water.本發明為一種微針裝置,其係具備基板、設置於上述基板上之微針、附著於上述微針上及/或基板上之生理活性組成物之微針裝置,上述生理活性組成物含有選自甘油、乙二醇、丙二醇及1,3-丁二醇之至少1種多元醇、及生理活性物質,且實質上不含水。1...微針裝置2...微針基板3...微針4...貫通孔