Invention relates to synergistic therapeutical composition comprising meldonium acetylsalicylic acid addition salt as a corrector of endothelial disfunction and an inhibitor of HMG-CoA reductase for use in prevention and/or treatment of thrombosis.Izveidota sinerģ；iska terapeitiska kompoz&imacr；cija, kas ietver meldonija acetilsalicilsk&amacr；bes adit&imacr；vo s&amacr；li k&amacr； endoteli&amacr；l&amacr；s disfunkcijas korektoru un HMG-CoA redukt&amacr；zes inhibitoru, trombozes profilaksei un/vai &amacr；rst&emacr；&scaron；anai.
