THERAPY AND DIAGNOSIS OF DISEASE CHARACTERIZED BY ALTERATIONS IN THE DNA DAMAGE RESPONSE

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专利权人:

IFOM - FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE;UNIVERSITÀ DEGLI STUDI DI MILANO;ISTITUTO EUROPEO DI ONCOLOGIA S.R.L.

发明人:

Saverio MINUCCI,Mohamed ELGENDY,Riccardo CAZZOLI,Sebastiano PERI,Elisa FERRARI,Marco FOIANI

申请号：

US16615045

公开号：

US20200164047A1

申请日:

2018.05.21

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to at least one modulator of PP2A or at least one modulator of PP2A-like phosphatase or at least one modulator of PP2A and PP2A-like phosphatase or a combination of said modulators for use in the treatment of a disease characterized by an alteration in the DNA damage response. The present invention also relates to a method to identify a subject to be treated with a PP2A modulator comprising detecting in the genome of said patient a mutation in PP2A.

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中国工程科技知识中心

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http://www.ckcest.cn/home/