Christiaan Nicolaas KLIJN,James LEE,David Hugh STOKOE,Robert GENTLEMAN,Florian GNAD,Leonard David GOLDSTEIN,Juliann CHMIELECKI,Ryan J. HARTMAIER
申请号：
US16230223
公开号：
US20190218618A1
申请日:
2018.12.21
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention provides methods of identifying a subject having cancer, such as lung cancer, by analyzing expression levels of one or more NRF2 splice variants or NRF2 target genes. The invention also provides methods of treating cancer in a subject with a NRF2 pathway antagonist, wherein the subject expresses one or more NRF2 splice variants or overexpresses one or more NRF2 target genes.
