Refers to amino tropane derivative compounds of formula (i) wherein R1, R2 and R3 are each H Lower alkyl, optionally substituted with lower alkoxy, halogen, alkyl or cycloalkyl s Lower. Preferred compounds are: 2 - methoxy - (N - (1S, 2S, 5R) - 5 - methyl - 2 - phenyl - 8 - aza Bicyclo [3.2.Oct - 2 - 1] methylsulfanyl) - il - 6 - 4 - 2 - trifluoromethyl - benzamide cyclopropyl - (N - (1RS, 5SR 2RS) - 4 - methyl - 2 - phenyl - 8 - aza Bicyclo [3.2.1] oct - 2 - il - 4 - trifluoromethyl) - benzamide 2 methoxy - 3 - (n-methyl-n - (1RS, 5SR 2RS) - 4 - methyl - 2 - phenyl - 8 - aza Bicyclo [3.2.1] oct - 2 - il - 4 - trifluoromethyl) - benzamide among others. It also relates to a preparation method and a Pharmaceutical composition.These compounds are inhibitors of the Glycine TRANSPORTER 1 (GlyT - 1) being useful in the treatment of schizophrenia, Dementia disorders, Alzheimers diseaseSE REFIERE A COMPUESTOS DERIVADOS DE AMINO-TROPANO DE FORMULA (I) DONDE R1, R2 Y R3 SON CADA UNO H, ALQUILO INFERIOR OPCIONALMENTE SUSTITUIDO CON HALOGENO, ALCOXI INFERIOR, CICLOALQUILO O S-ALQUILO INFERIOR. SON COMPUESTOS PREFERIDOS: 2-METOXI-N-((1S,2S,5R)-8-METIL-2-FENIL-8-AZA-BICICLO[3.2.1]OCT-2-IL)-6-METILSULFANIL-4-TRIFLUOROMETIL-BENZAMIDA 2-CICLOPROPIL-N-((1RS,2RS,5SR)-8-METIL-2-FENIL-8-AZA-BICICLO[3.2.1]OCT-2-IL)-4-TRIFLUOROMETIL-BENZAMIDA 2-METOXI-6-METIL-N-((1RS,2RS,5SR)-8-METIL-2-FENIL-8-AZA-BICICLO[3.2.1]OCT-2-IL)-4-TRIFLUOROMETIL-BENZAMIDA ENTRE OTROS. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PREPARACION Y A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DEL TRANSPORTADOR DE GLICINA 1 (GlyT-1) SIENDO UTILES EN EL TRATAMIENTO DE ESQUIZOFRENIA, TRASTORNOS DE DEMENCIA, ENFERMEDAD DE ALZHEIMER
