Provided is an agent that reduces the risk of disease onset resulting from non-dipper type intra-day blood pressure fluctuations and that can reduce the onset of disease resulting from intra-day blood pressure fluctuation risk and prone to occur towards the morning when early morning systolic blood pressure significantly decreases from that of the night time in humans having a particular non-dipper type intra-day blood pressure fluctuation pattern, particularly healthy individuals exhibiting normal SBP and DBP values. The agent is characterized by containing: a hydrolysate containing VPP and IPP and obtained by hydrolyzing animal milk protein; or a concentrate thereof.