Yale University ;Ospedale San Raffaele Srl ;Fondazione Telethon
发明人:
FLAVELL Richard A.,GAGLIANI Nicola,GREGORI Silvia,HUBER Samuel,MAGNANI Chiara Francesca,RONCAROLO Maria Grazia
申请号:
US201715711194
公开号:
US2018119099(A1)
申请日:
2017.09.21
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
The invention is based upon the discovery that T regulatory type 1 (Tr1) cells express particular cell surface markers that allow for their selection, enrichment, isolation, purification and administration. The ability to use the particular markers described herein to select, enrich, isolate, purify and administer Tr1 cells allows for improved methods of Tr1 therapies for treating a wide variety of diseases and disorders.