Saad Ali;Nicholas J. Cotton;Steven W. Astorino;Emma J. Wright
发明人:
Nicholas J. Cotton,Emma J. Wright,Steven W. Astorino,Saad Ali
申请号：
US12484274
公开号：
US09616155B2
申请日:
2009.06.15
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Fixation devices for tissue repair, for example sutures, surgical arrows, staples, darts, bolts, screws, buttons, anchors, nails, rivets, or barbed devices comprise at least one of angiogenic material； angiogenic precursor material which is capable of breaking down in vivo to form angiogenic material； or tissue-engineered material, which tissue-engineered material is capable of producing angiogenic material. In a preferred form, the material is incorporated into a polymer matrix having predetermined hydrophobicity to allow controlled release of angiogenic materials such as butyric or hydroxybutyric acid or salts thereof. Polymer matrix compositions comprising angiogenic materials and methods for tissue repair are also provided.
