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Carboxylic acid ALA esters
专利权人:
Photocure ASA
发明人:
Jon Erik Brænden,Colin Barry Charnock,Aslak Godal,Jo Klaveness,Nils Olav Nilsen
申请号:
US14419125
公开号:
US09249086B2
申请日:
2013.08.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to new derivatives of 5-aminolevulinic acid (5-ALA) and their use as photosensitizing agents. In particular, it relates to compounds of general formula I and their pharmaceutically acceptable salts, to methods for preparing such compounds and their medical and cosmetic use, for example in methods of photodynamic therapy and diagnosis:whereinR1 represents a hydrogen atom or an optionally substituted alkyl or cycloalkyl group;R2, each of which may be the same or different, represents a hydrogen atom or an optionally substituted alkyl group; andX is a linking group.
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