Sanjay Jagdish DESAI,Jayprakash Ajitsingh PARIHAR,Alpesh Pravinchandra SHAH
申请号：
US15585605
公开号：
US20170320862A1
申请日:
2017.05.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.
