The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.本發明提供一種藉由投藥給一病患一有效量的本發明的一前驅藥化合物來持續輸送一含有內醯胺、醯亞胺、醯胺、磺醯胺、胺甲酸酯或尿素的母體藥之方法，其中在投藥給該病患上，來自該前驅藥的該母體藥的釋放是持續的釋放。適合於使用在本發明的方法中的前驅藥化合物是經由羰基連結的前驅藥部分所衍生的母體藥的不穩定綴合物。本發明的前驅藥化合物可被用於治療該含有內醯胺、醯亞胺、醯胺、磺醯胺、胺甲酸酯或尿素的母體藥作為一治療是有用的任何病況。
