The present invention relates to an apparatus and method for improving the delivery of desirable substances across a membrane utilizing a varying electromagnetic energisation profile. More particularly, the invention provides methods for modifying the cellular environment of such membranes and the behaviour of substance molecules during transport across a membrane. In use, the profile will have application in, enhancing transmembrane delivery of substances (such as pharmaceuticals, nutraceuticals, biopharmaceuticals and cosmeceuticals), and/or enhancing or expanding a cellular cohort of membranes and surrounding tissues.
