PROBLEM TO BE SOLVED: To provide a radiopharmaceutical administration device which is advantageous in reducing external dimensions and saving space required for installation. SOLUTION: A container holder 122 for holding a shielded container 5 of a radiopharmaceutical 27, flow path switching members 33a, 33b constituting a part of a flow path connected to a vial 7 housed in the container holder 122,. 33c, the first syringe 36a, the second syringe 36b, the saline flow path 31a, the radioactive flow path 31b, the flow path constituent member arrangement portion 14 to which the air vented filter 32 is attached, the shielding member 21 for the radiation emitted from the radiopharmaceutical, The device includes a device housing 20 of a shielding member, and the shielding member 21 has a shielding wall 21g whose upper surface is partially lower than other portions according to the size of the flow path forming member, and is outside the shielding member 21. The radioactive flow path 31b is loosely inserted above the shielding wall 21g. [Selection diagram] Fig. 3【課題】外形寸法を小型化し、設置に必要な空間の省スペース化に有利な放射性薬剤投与装置を提供する。【解決手段】放射性薬剤27の遮蔽容器5を保持する容器ホルダ122、容器ホルダ122内に収容されているバイアル瓶7に接続される流路の一部を構成する流路切換部材33a、33b、33c、第一シリンジ36a、第二シリンジ36b、食塩水流路31a、放射性流路31b、エアベンテッドフィルタ32が取り付けられる流路構成部材配置部14、放射性薬剤から放出される放射線の遮蔽部材21、遮蔽部材の装置ハウジング20を備え、遮蔽部材21は、上面の一部が流路構成部材の大きさに応じて他の部分よりも低い遮蔽壁21gを有し、遮蔽部材21の外部であって遮蔽壁21gの上方に放射性流路31bが遊挿される。【選択図】図3