Nagy, Eszter,Von Gabain, Alexander,Berger, Manfred,Senn, Beatrice,Schunn, Michael,Meinke, Andreas
申请号：
AU2013203639
公开号：
AU2013203639A1
申请日:
2013.04.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013203639A120130502.pdf#####Abstract The present invention relates to a peptide consisting of one antigen of Streptococcus pyogenes (S. pyogenes) of any of the SEQ ID NOS: 1 to 7 or a functional active variant thereof, optionally further consisting of additional amino acid residue(s)； a nucleic acid coding for the same； a pharmaceutical composition, especially a vaccine, comprising said peptide or said nucleic acid； an antibody or functional active fragment thereof specifically binding to the antigen； a hybridoma cell line which produces said antibody； a method for producing said antibody； a pharmaceutical composition comprising said antibody； the use of said peptide or said nucleic acid for the manufacture of a medicament for the immunization or treatment of a subject； the use of said antibody or functional fragment thereof for the manufacture of a medicament for the treatment of an infection； a method of diagnosing a S. pyogenes infection； a method for identifying a ligand capable of binding to said peptide； and the use of said peptide for the isolation and/or purification and/or identification of an interaction partner of the peptide.
