Eduard LUSS-LUSIS,John P. CAESAR, JR.,Majed FAWAZ,Kwame Wiredu NTI-ADDAE,Patrick Raymond CONNELLY,Brian R. MCCLAIN,Ales MEDEK,Hai MIAO,Ping YIN,Yuegang ZHANG,Mark STROHMEIER
申请号：
MX2017004631
公开号：
MX370450B
申请日:
2015.10.07
申请国别(地区):
MX
年份:
2019
代理人:
摘要：
The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-ox oquinoline-3-carboxamide (Compound 1) and a co-former and methods for their preparation. The present disclosure further relates to pharmaceutical compositions comprising the co-crystal forms, as well as methods of treatment therewith and kits.La presente invención se refiere a co-cristales que comprenden N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquin olino-3-carboxamida (Compuesto 1) y un co-formador, y a métodos para su preparación. La presente invención se refiere además a composiciones farmacéuticas que comprenden las formas de co-cristal, así como a métodos de tratamiento con las mismas y kits.
