3-SUBSTITUTED-[1,2,3]-BENZOTRIAZINONE COMPOUND FOR ENHANCING GLUTAMATERIC SYNAPTIC RESPONSES

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专利权人:

发明人:

CORDI, ALEXIS,ROGERS, GARY,MUELLER, RUDOLF

申请号：

MYPI 20092796

公开号：

MY154877A

申请日:

2007.12.28

申请国别(地区):

MY

年份:

2015

代理人:

摘要：

THIS INVENTION RELATES TO THE PREVENTION AND TREATMENT OF CEREBRAL INSUFFICIENCY, INCLUDING ENHANCEMENT OF RECEPTOR FUNCTIONING IN SYNAPSES IN BRAIN NETWORKS RESPONSIBLE FOR HIGHER ORDER BEHAVIORS. THESE BRAIN NETWORKS ARE INVOLVED IN COGNITIVE ABILITIES RELATED TO MEMORY IMPAIRMENT, SUCH AS IS OBSERVED IN A VARIETY OF DEMENTIAS, AND IN IMBALANCES IN NEURONAL ACTIVITY BETWEEN DIFFERENT BRAIN REGIONS, AS IS SUGGESTED IN DISORDERS SUCH AS PARKINSONS DISEASE, SCHIZOPHRENIA AND AFFECTIVE DISORDERS. IN A PARTICULAR ASPECT, THE PRESENT INVENTION RELATES TO A COMPOUND USEFUL FOR TREATMENT OF SUCH CONDITIONS, AND METHODS OF USING THIS COMPOUND FOR SUCH TREATMENT.

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