CLARKE, DAVID KIRKWOOD,HENDRY, ROGER MICHAEL,UDEM, STEPHEN A.,PARKS, CHRISTOPHER LEE
申请号:
CA2561245
公开号:
CA2561245C
申请日:
2005.04.05
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention broadly relates to the synergistic attenuation ofvesicular stomatitisvirus (VSV). More particularly, the invention relates to the identification ofcombined mutationclasses which synergistically attenuate the pathogenicity of VSV vectors inmammals andimmunogenic compositions thereof.