DERIVES D'AZITHROMYCINE CONTENANT UN ION PHOSPHONIUM UTILISES EN TANT QU'AGENTS ANTICANCEREUX

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专利权人:

RISING TIDE FOUNDATION

发明人:

SPAREY, TIM,RATCLIFFE, ANDREW,HALLETT, DAVID,STEVENSON, BRETT,COCHRANE, EDWARD,FROIDBISE, ALEXANDRE

申请号：

CA3079368

公开号：

CA3079368A1

申请日:

2018.04.20

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds. The compounds comprise an ion of formula (I): wherein either Z1 is and Z2 is R4b； or Z2 is and Z1 is R2b.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/