Topical germicidal compositions for application to the epidermis, e.g., hands, arms, legs, face, scalp as well as other body areas, which topical germicidal compositions provide a skin sanitization benefit due to the presence of a large amount of alcohol, yet which impart skin treatment benefits to treated dermal surfaces. The topical germicidal compositions necessarily comprise at least 50% wt. of a C1-C4 monohydric alcohol, preferably ethanol, water and lipid based nanoparticles.