Deoxynojirimycin analogues and their use as glucosylceramidase inhibitors

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专利权人:

ゲンザイム コーポレーション

发明人:

アーツ ヨハンネス マリア フランシスカス ヘラルダス

申请号：

JP2012091984

公开号：

JP5730808B2

申请日:

2012.04.13

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The invention provides a new class of deoxynojirimycin analogues, or pharmaceutically acceptable salts thereof which can suitably be used for the treatment of a disease selected from the group consisting of insulin resistance, Gauger disease, inflammatory diseases, hyperpigmentation and/or inflammatory skin conditions, overweight and obesity, lysosomal storage disorders, fungal diseases, melanoma and other tumors, and microbacterial infections. The invention further provides a pharmaceutical composition comprising said deoxynojirimycon analogue, or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.

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