The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.本發明係有關經取代的酮基吡啶衍生物及彼等之製備方法,以及彼等供製備用於治療及/或預防疾病(特別是心血管疾病,較佳血栓或血栓栓塞性疾病)和水腫以及眼疾病)的藥劑之用途。