Jorge Luis BAUTISTA GÓMEZ,Nallely De Sofia KANTER SILVANO,Eliseo CHULIN LÓPEZ
申请号：
MX2017002622
公开号：
MX2017002622A
申请日:
2017.02.23
申请国别(地区):
MX
年份:
2018
代理人:
摘要：
The present invention relates to a topical gel with antiseptic and healing functions from the Leaf of Seaw (still to be identified) and Donkey Ear (Elephantopus Mollis) as an alternative in the treatment of wounds, infections, and minor irritations, thus aiming to provide an efficient alternative in traditional medicine. The gel comprises ketone extracts processed (at 65°C for four hours) from 30gr. of leaves of both plants. Said leaves concentrate and resuspend in distilled water at concentrations of up to 1000 mg/ml and integrate into a water-based gel, subsequently tested on Staphylococcus Aureus and Candida Utilis by plaque and sensor-disc casting technique, throwing a high antimicrobial effectiveness on Staphylococcus Aureus. In addition, the gel is determined as an antiseptic agent at four mg/ml and a high bioavailability (distribution in the skin). Further, it comprises 70% extract of plants (active substance), 25% Carbopol, 2% Triethanolamine (providing consistency), and 3% gl ycerin (providing moisture). Finally, it applies to four mg/ml extract of both plants, thus providing high effectiveness and low concentration, making its origin costs economical and profitable.La pérdida de eficacia de los antibióticos lleva a buscar nuevas alternativas en la medicina tradicional. Por lo cual se "genera un gel tópico con funciones antísépticas y cicatrizantes a partir de las plantas Hoja de Seaw (por identificar) y Oreja de Burro (Elephantopus mollis)" como alternativa en el tratamiento de heridas, infecciones e irritaciones leves. Para lo que se procesaron extractos cetónicos (a 65ºC por 4 horas) a partir de 30 gr. de hojas de ambas plantas, Estos se concentran y se resuspenden en agua destilada a concentraciones de 2, 3, 4, 5, 125, 250, 500 y 1000 mg/ml e integradas a un gel base agua, posteriormente probadas sobre Staphilococcus aureus y Candida utilis por la técnica de vaciado en placa y sensidiscos, Arrojando una alta efectividad antimicrobiana sobre Staphilococc
