The present invention relates to a bioadherent substrate comprising a medical gel having a plurality of reactive members of a specific binding pair adapted to be attached on a surface of the medical gel, said reactive members being capable of forming covalent bonds with a plurality of complementary reactive members of the specific binding pair via a click chemistry reaction,wherein the click chemistry reaction is selected from the group consisting of a Diels-Alder reaction and a thiol-ene reaction and to a method of forming the medical gel.