CZAPLEWSKI LLOYD GEORGE,HAYDEN DAVID JOHN,BROWN DAVID RYALL,COLLINS IAN
申请号:
IN5693/CHENP/2008
公开号:
IN281872B
申请日:
2008.10.22
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The use of a compound which is a substituted benzamide or pyridylamide of formula (I) or a salt, hydrate, or solvate thereof, in the manufacture of a medicament for use in treating bacterial infection: wherein R represents hydrogen or 1, 2 or 3 optional substituents Wis=C(R1)-or=N- Ri is hydrogen and R2 is hydrogen, methyl, or fluorine or R, and R2 taken together are -CH2-, -CH2CH2-, -0-, or, in either orientation, -0-CH2- or -OCH2CH2- R3 is a radical of formula -(Alk1)m-(Z)p-(Alk2)n-Q wherein m, p and n are independently 0 or 1, provided that at least one of m, p and n is 1, Z is -0-, -S-, -S(O)-, -S(02)-, -NH-, -N(CH3)-, -N(CH2CH3)-, -C(=0}-, -0-(C=0)-, -C(=0)-0-, or an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms or an optionally substituted divalent bicyclic heterocyclic radical having 5 to 10 ring atoms Alk1 and Alk2 are optionally substituted C^Ce alkylene,