드 종, 잔 코르넬리우스,포우키에르, 로날두스 아드리아누스 마리아,반 덴 호겐, 베르나우데타 게라르다,오스테르하우스, 알베르투스 도미니쿠스 마르셀리누스에라스무스,그로엔, 쟌
申请号：
KR1020117020851
公开号：
KR1014123170000B1
申请日:
2002.01.18
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV). Described are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. Also described is mammalian MPV, subgroups and variants thereof, and genomic nucleotide sequences of different isolates of mammalian metapneumoviruses, in particular human metapneumoviruses. The use of the sequence information of different isolates of mammalian metapneumoviruses for diagnostic and therapeutic methods is provided. Nucleotide sequences encoding the genome of a metapneumovirus or a portion thereof, including both mammalian and avian metapneumovirus are described. Also provided are chimeric or recombinant viruses encoded by said nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.본원 발명은 바이러스학 분야에 관계한다. 본원 발명은 파라믹소비리데(Paramyxoviridae) 과(科)의 아과 뉴모비리네(Pneumovirinae)에 속하는 네거티브-센스 단일 쇄 RNA 바이러스(MPV) 분리체를 제공하고, 메타뉴모바이러스(Metapneumovirus) 속(genus)에 계통학적으로 상응하는 것으로 확인되었다.
