The object of the present invention is to provide a compound with PIM inhibitory activity. As the present invention, for example, a 1,3,4-oxadiazolone compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof, or a solvate thereof can be cited. The compounds of the present invention have PIM inhibitory activity. In addition, since the compound of the present invention has PIM inhibitory activity, it is useful as a therapeutic agent for systemic lupus erythematosus and lupus nephritis.本發明之目的在於提供一種具有PIM抑制活性之化合物。作為本發明，例如可列舉：以下之式[1]所表示之1,3,4-㗁二唑酮化合物或其醫藥上所容許之鹽、或者其溶劑合物。本發明化合物具有PIM抑制活性。又，本發明化合物由於具有PIM抑制活性，故而作為全身性紅斑狼瘡、狼瘡性腎炎等之治療劑有用。
