< Topic > The fact that you design produce the polypeptides molecules which include 4 copy TKPR fragments leading, improving the immunity performance and anti- tumor activity efficiently, furthermore it develops the applied possible anti- tumor medicine and the immunity strengthening medicine clinically.Solutions This invention is published one 4 copy divergence peptides and its application, it has the potential capacity where structure of particular divergence peptide as for formula (X A-X B-X C-X D-X1) 4 > (K-X2) with 2 >K-X3, as for particular divergence peptide action of clear tumor growth control and immunity strengthening is shown with animal test, develops as the clinical anti- tumor medicine and the immunity strengthening medicine.< Selective figure >It is not【課題】 4コピーTKPR断片を含むポリペプチド類分子を設計作製することと通じて、その免疫機能及び抗腫瘍活性を効率的に向上させて、さらに臨床に応用可能な抗腫瘍薬と免疫強化剤を開発する。【解決手段】 本発明は、一つの4コピー分岐ペプチド及びその応用を公表され、当該分岐ペプチドの構造通式は(XA-XB-XC-XD-X1)4>(K-X2)2>K-X3で、当該分岐ペプチドは動物試験で明らかな腫瘍成長抑制と免疫強化の作用が示され、臨床抗腫瘍薬及び免疫強化剤として開発する潜在力を持っている。【選択図】なし
