GENE ENCODING A MULTIDRUG RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7P15-21 AND USES THEREOF

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专利权人:

发明人:

Markus M. Frank,Mohamed H. Sayegh

申请号：

US13938938

公开号：

US20130287785A1

申请日:

2013.07.10

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention relates to an MDR family P-glycoprotein located on human chromosome 7p15-21, polynucleotide sequences encoding this P-glycoprotein and fragments thereof. This gene is utilized in methods for assessing cancer cell susceptibility to therapies directed against multidrug resistance, and for the design of diagnostic and therapeutic methods relating to cancer multidrug resistance. The invention also relates to methods for determining whether a test compound may inhibit multidrug resistance.

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中国工程科技知识中心

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http://www.ckcest.cn/home/