Rappaport Family Institute for Research in the Medical Sciences
发明人:
Yuval Shaked
申请号：
US16712816
公开号：
US20200316173A1
申请日:
2019.12.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method is provided for treating a cancer patient non-responsive to treatment with a immune checkpoint inhibitor (ICI) by treating the patient with said ICI in combination with an agent that blocks the activity of a dominant factor selected among the plurality of host-driven resistance factors generated in response to treatment of the cancer patient with the ICI, these factors having a fold-change predictive of a non-favorable response of the cancer patient to the treatment with the ICI.
