Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" (RU)
发明人:
Шустер Александр Михайлович (RU),Хамитов Равиль Авгатович (RU),Аббасова Светлана Георгиевна (RU),Фабричный Игорь Павлович (RU),Потеряев Дмитрий Александрович (RU),Бадэ Вероника Николаевна (RU)
申请号：
RU2016148710
公开号：
RU2016148710A
申请日:
2016.12.13
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
The invention relates to the field of medicine and can be used in the pharmaceutical industry for producing a drug for treating a disease correlated with macular oedema associated with VEGF-A overexpression. An F(ab)2-fragment of anti-VEGF-A antibody is provided as active substance of the drug for treating a disease correlated with macular oedema caused by VEGF-A overexpression. Moreover, the aforementioned dimer can comprise additional amino acid sequences, which improve the pharmacological properties thereof. The use of the present invention makes it possible to improve the ease of use of the anti-VEGF-A-therapy for macular oedema.
