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SULFANYLAMIDE DERIVATIVES, USES THEREOF AND COMPOSITIONS COMPRISING THEM
专利权人:
Meir Bialer
发明人:
Meir Bialer,Boris Yagen,Hen Naama
申请号:
US13497434
公开号:
US20120264827A1
申请日:
2010.09.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention concerns a family of sulfanilamide derivatives of formula (I) as anticonvulsant agents, where R is selected from optionally substituted C4-C9 alkyl, optionally substituted C6-C10 aryl, optionally substituted C6-C10 alkylenearyl and optionally substituted C5-C10heteroaryl R2 is selected from —H and optionally substituted C1-C6 alkyl each of R3 and R4, independently of each other, is selected from —H, optionally substituted C1-C6 alkyl, optionally substituted C6-C10 aryl and optionally substituted C5-C10 heteroaryl n is 0, 1, 2, 3 or 4. The derivatives have been prepared and their anticonvulsant profile was evaluated for the control of epileptic seizures.
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