The present invention relates to a composition containing a masterwort (Peucedanum Ostruthium) extract as an active ingredient. The composition of the present invention exhibits effects of reducing the amount of endothelin 1 by containing a masterwort extract, and reducing the overexpression of NK1R and EDN1 genes. Therefore, the masterwort extract of the present invention can exhibit, by said effects, skin homeostasis maintenance and anti-stress effects, and thus can be widely used as acomposition for maintaining skin homeostasis in the pharmaceutical or cosmetic field.
