Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide or a pharmaceutically acceptable derivative thereof in the manufacture of a medicament for the treatment of acute exacerbations of chronic obstructive pulmonary disease. Treatment may involve a single dose of the active ingredient by oral administration.Uso de 3-[5-amino-4-(3-cianobenzoil)pirazol-1-il]-N-ciclopropil-4-metilbenzamida para el tratamiento de las exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica.