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Beta-krystallinsk form av argininsaltet til perindopril, en prosess for dets fremstilling og farmasøytiske sammensetninger inneholdende dette
专利权人:
Les Laboratoires Servier
发明人:
Coquerel, Gérard,Lefebvre, Loïc,Souvie, Jean-Claude,Authouart, Pascale
申请号:
NO20083506
公开号:
NO341238B1
申请日:
2008.08.13
申请国别(地区):
NO
年份:
2017
代理人:
摘要:
Beta crystalline form of perindopril arginine salt (I), characterized by the X-ray diffraction diagram on powder, measured by a diffractometer (copper anticathode) and exhibited a Bragg angle 2 theta (expressed in percentage in relation to the most intense line), an interreticular distance (d), an intensity and a relative intensity, as given in table of the specification, is new. Beta crystalline form of perindopril arginine salt of formula (I), characterized by the X-ray diffraction diagram on powder, measured by a diffractometer (copper anticathode) and exhibited a Bragg angle 2 theta (expressed in percentage in relation to the most intense line), an interreticular distance (d), an intensity and a relative intensity, as given in table of the specification, is new. Independent claims are included for: (1) a composition comprising (I) in combination with inert and nontoxic vehicles and (2) the preparation of (I). ACTIVITY : Cardiovascular-Gen Hypotensive Cardiant. MECHANISM OF ACTION : Angiotensin I converting enzyme inhibitor. No biological data given.
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