Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel and ethinyl estradiol, comprising an acrylic polymer matrix. Methods of making and using such systems also are described.本發明闡述用於經皮投與左炔諾孕酮(levonorgestrel)及乙烯雌二醇之經皮藥物遞送系統,其包括丙烯酸系聚合物基質。亦闡述製備及使用該等系統之方法。