QUEMENEUR, LAURENCE,PIETROBON, PATRICIA J.,LONDONO-HAYES, PATRICIA,HAUSER, STEVEN
申请号：
CA2986025
公开号：
CA2986025A1
申请日:
2016.05.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The disclosure relates to generally to the field of therapeutic and/or protective vaccination against Clostridium dificile (C. difficile). More specifically, it relates to methods for immunizing a host against C. difficile strains expressing C. difficile binary toxin (CDT) and strains not expressing CDT. These methods involve the administration to a host of an immunogenic composition comprising inactivated purified C. difficile Toxin A and purified Toxin B. The purified C. difficile toxins may be derived from a C. difficile strain that does not express CDT.
