HANGZHOU HUADONG MEDICINE GROUP PHARMACEUTICAL RESEARCH INSTITUTE CO.; LTD
发明人:
Yubin LV,Jianming YIN,Xuehui HUANG,Bangliang LI
申请号:
US15571582
公开号:
US20180134668A1
申请日:
2016.05.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are crystal forms K, E, F and G of the dimaleate of the compound as shown in formula I, and preparation methods and uses thereof. The crystal forms K, E, F and G have superior storage stability and solubility, so that they are more suitable for being used as the drug substance for drug product preparations.