DEL RÍO PERICACHO, JOSÉ LUIS,VILA TUSELL, XAVIER,SÁNCHEZ IZQUIERDO, FRANCISCO
申请号：
FI20125038
公开号：
FI124449B
申请日:
2012.01.13
申请国别(地区):
FI
年份:
2014
代理人:
摘要：
. Process for preparing a receptor antagonist of endothelin # Process for the preparation of a compound of formula (I), or a salt or solvate thereof including a hydrate, wherein: R {sub, 1} is CH {? sub, 2} CH {sub, 2} OH or CH {sub, 2} CH {sub, 2} R {sub, 2}； R {sub, 2} is -OR {sub, prot}, a precursor or a precursor -OH -OR {sub, prot}； and R {sub, prot} is a protecting group of alcohols. The process comprises a Mitsunobu type coupling, which is introduced by the OR group {sub, 1} is introduced.
