ARMSTRONG, Nicholas J.,BOWEN, Mayumi N.,MAA, Yuh-Fun
申请号：
AU2018203876
公开号：
AU2018203876A1
申请日:
2018.06.01
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018203876A120180621.pdf#####Abstract The present application discloses high-concentration monoclonal antibody formulations suitable for subcutaneous administration, e.g. via a pre-filled syringe. In particular, it discloses a formulation comprising a spray dried monoclonal antibody at a concentration of about 200 mg/mL or more suspended in a non-aqueous suspension vehicle where the viscocity of the suspension vehicle is less than about 20 centipoise. Also disclosed are: a subcutaneous administration device with the formulation therein, a method of making the formulation, a method of making an article of manufacture comprising the suspension formulation, use of the formulation in the preparation of a medicament, and a method of treating a patient with the formulation. 10331602_1 (GHMatters) P98606.AU.1
