Hermetic closing plug for a sealed sterile vial containing medical or nutritional active substances, suitable for the sterile connection to a container of liquid diluent solution, and sterile connection system using said closing plug
A closing plug for a sealed sterile vial containing medical or nutritional active substances, which is suitable for the sterile connection to a container of liquid diluent solution. There is also described a sterile connection system between a sealed sterile vial closed by means of a plug and a tube for drawing said active substances, for mixing them with a liquid diluent solution inside a sterile container. The plug requires an internal sterile chamber in which, upon the piercing of an outer film for sealing the plug, a compressible protection cap of a piercing tip of the tube is inserted, which abuts against a seat of the sterile chamber allowing the tip to pierce the end wall of the protection cap and then the inner membrane of the closing plug. An intermediate pierceable membrane placed on the seat of the internal chamber of the vial may be included.