Use of erythrocytes containing arginine deiminase for the preparation of amedicinal productfor lowering the plasma concentration of arginine in vivo. The erythrocytesbehave asbioreactors, in which the plasma arginine entered the erythrocytes containingargininedeiminase by passive diffusion is degraded by the arginine deiminase. Said userelates inparticular to the treatment of arginine-dependent tumors, such ashepatocarcinoma andmalignant melanoma, or inhibition of the synthesis of nitric oxide, and theprevention and/ortreatment of septic shock.
