Zhaozhong J. Jia,Chandrasekar Venkataramani,Wolin Huang,Mukund Mehrotra,Yonghong Song,Qing Xu,Shawn M. Bauer,Jack W. Rose,Brian Kane,Anjali Pandey
申请号：
US13658730
公开号：
US08952027B2
申请日:
2012.10.23
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkins Lymphoma.
