PROBLEM TO BE SOLVED: To provide a coated powder comprising a protein or peptide component, or pyrroloquinoline quinones which are hard to cause discoloration even if they contact the tongue or tissue in a mouth physically for a long time, and are excellent in storage stability and tableting properties, and to provide a production method thereof, as well as to provide a composition comprising the coated powder.SOLUTION: The invention provides a coated powder containing a nucleus containing pyrroloquinoline quinones, a first coating layer which coats at least a part of the surface of the nucleus and contains a water-insoluble substance, and a second coating layer which coats at least one part of the surface of the first coating layer and contains oil and fat.COPYRIGHT: (C)2015,JPO&INPIT【課題】タンパクやペプチド性の成分、又は舌や口の中の組織と物理的に長時間接触しても変色が生じにくく、保存安定性及び打錠性に優れる、ピロロキノリンキノン類を含む被覆粉末及びその製造方法、並びに被覆粉末を含む組成物を提供することを目的とする。【解決手段】 ピロロキノリンキノン類を含む核と、該核の表面の少なくとも一部を被覆し、水難溶性物質を含む第1の被覆層と、該第1の被覆層の表面の少なくとも一部を被覆し、油脂を含む第2の被覆層と、を含む、被覆粉末。【選択図】なし
